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Herpes Cure And Treatment

Novel Polymorphs Valacyclovir Hydrochloride

Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and pharmaceutical compositions containing these. In this invention the novel polymorphs of the valacyclovir hydrochloride and methods for preparing these novel polymorphs are provided. A process for the preparation of valacyclovir hydrochloride in monohydrate form, as well as of several other hydrate and anhydrous forms, and novel hydrate polymorphic forms obtainable by said process. A process for the preparation of valacyclovir hydrochloride in monohydrate form, as well as of several other hydrate and anhydrous forms, and novel hydrate polymorphic forms obtainable by said process.

Abstract: Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and pharmaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydrate. Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and pharmaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydrate.

Patents By Inventor Michael Yuzefovich

Provided are novel crystalline forms of valacyclovir hydrochloride denominated forms VIII, IX, X, XI, and XII and methods of making them. Also provided is a novel method for making valacyclovir hydrochloride in crystalline form V.

It has been found that valacyclovir hydrochloride is moderately soluble in water. 0031Each of the salts provided by the present invention is also characterised herein as one or more novel polymorphic forms and as such there is also provided by the present invention new polymorphic forms of valacyclovir mesylate, valacyclovir phosphate, valacyclovir maleate, valacyclovir fumarate, valacyclovir tartrate and valacyclovir citrate. Provided are novel crystalline forms of valacyclovir hydrochloride denominated forms VIII, IX, X, XI, and XII and methods of making them. US4957924 (Expiry: Dec 23, 2009) : Which covers Valacyclovir as product. Ranbaxy has manufactured the Valacyclovir hydrochloride 500 mg and 1 g tablets from it’s New Jersey based subsidiary Ohm Laboratories. Provided are novel polymorphs and pseudopolymorphs of valacyclovir hydrochloride and phamaceutical compositions containing these. Also provided are methods for making the novel polymorphs and pseudopolymorphs, which include valacyclovir hydrochloride monohydrate and valacyclovir hydrochloride dihydr.

Filiz Sahpaz Cerit

Inventions related to valacyclovir hydrochloride polymorphic. A process for the preparation of valacyclovir hydrochloride in. forms, and novel hydrate polymorphic forms obtainable by said process. Provided arc novel polymorphs and pseudopolymorphs of Val acyclovir hydrochloride and pharmaceutical composi-tiinis containing these. Human plasma paraoxonase-1 (PON1) , a polymorphic high-density lipoprotein (HDL) -associated enzyme, synthesized primarily in liver and secreted to associate with HDL, hydrolyzes a number of lactones, including HCTL 1517. Cloning and expression analysis of a novel human serine hydrolase with sequence similarity to prokaryotic enzymes involved in the degradation of aromatic compounds.

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Herpes Cure
Herpes Cure