Herpes Cure And Treatment

Valaciclovir Vs Aciclovir

Valacyclovir (Valtrex) comparative analysis valacyclovir vs acyclovir, valacyclovir vs famciclovir. Acyclovir (Zovirax) versus. Valacyclovir (Valtrex) versus. The antiviral medications available in pill form acyclovir, valacyclovir, famciclovir have been specifically developed for the treatment of genital herpes.

The efficacy of valacyclovir and acyclovir on genital herpes simplex virus (HSV) shedding was assessed in a double-blind, 3-period crossover trial. Valaciclovir versus acyclovir in patient-initiated treatment of recurrent genital herpes: a randomized, double-blind clinical trial. Valtrex vs Acyclovir for herpes suppression? Why would my doctor suggest i switch from valacyclovir to acyclovir out of the blue? i barely take the stuff for hsv 2 on my elbow, since i quit taking it my outbreaks from sun exposure have gotten milder. 1 Answer (question resolved) – Posted in: acyclovir, valacyclovir – Answer: Valacyclovir (Valtrex) and acyclovir (Zovirax) are antiviral drugs that.

Valacyclovir And Acyclovir For Suppression Of Shedding Of Herpes Simplex Virus In The Genital Tract

Valaciclovir, the l-valyl ester of acyclovir, is rapidly and almost completely converted to acyclovir in vivo and gives three- to fivefold increases in acyclovir bioavailability. 03, respectively) compared with acyclovir; median pain durations were 38 and 44 days, respectively, versus 51 days for acyclovir. Valaciclovir is a prodrug, an esterified version of aciclovir that has greater oral bioavailability (about 55) than aciclovir (1020). It is converted by esterases to the active drug aciclovir, as well as the amino acid valine, via hepatic first-pass metabolism.

Valacyclovir provides a high bioavailability of acyclovir, 3- to 5-fold higher than that obtained with oral acyclovir, and it is equivalent to plasma levels achieved with doses of intravenous acyclovir (see Table 1). Tyring, et al. conducted a comparison trial of valacyclovir vs. famciclovir, which did not reveal any significant differences between either antiviral in the treatment of herpes zoster.

Valacyclovir: An Overview


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