Herpes Cure And Treatment

Viral Meningitis Treatment Acyclovir Dose

The management, prognosis, and prevention of viral meningitis in children will be discussed here. Acyclovir dosing in the neonatal period and beyond. Includes: indications, dosage, adverse reactions, pharmacology and more. Acyclovir is an antiviral drug active against herpes viruses. Overall mortality at 12 months for patients treated with acyclovir was 25 compared to 59 for patients treated with vidarabine.

Infants with meningitis frequently present with non-specific symptoms such as fever, irritability, lethargy, poor feeding, vomiting and diarrhoea. Aciclovir 20 mg/kg iv 8H (age 3m ) 500 mg/m2 iv 8H (age 3m-12y) 10 mg/kg iv 8H (age 12y). Benzylpenicillin 60mg/kg/dose (max 3g) , iv 4 hourly for 7 days. Viral meningitis treatment options, diagnosis, and images at Epocrates Online, the leading provider of drug and disease decision support tools. Viral meningitis is often assumed to be a largely benign disease. Rapid diagnosis by CSF RTPCR assays has allowed reductions in both hospital stays and antibiotic usage in patients admitted with enteroviral meningitis 2, 21, 28 and limited the use of acyclovir in patients with suspected HSV encephalitis. CEMA, many would advocate a high-dose immunoglobulin therapy, particularly for complications outside the CNS.

Clinical Practice Guidelines

Each 10 mL vial contains acyclovir sodium equivalent to 500 mg of acyclovir. The calculated dose should then be removed and added to any appropriate intravenous solution at a volume selected for administration during each 1 hour infusion. Therapy should be initiated as early as possible following onset of signs and symptoms of herpes infections. Although HSE is rare, mortality rates reach 70 in the absence of therapy and only a minority of individuals return to normal function. Herpes infection of the CNS, especially with HSV-2, can also cause both monophasic and recurrent aseptic meningitis, as well as myelitis or radiculitis. Symptoms from her earlier meningitis episodes lasted 3 to 10 days and subsequently cleared without any residual symptoms. On recovery, the patient had no neurological deficits and was discharged from the hospital on a prophylactic dose of acyclovir.

Empiric antimicrobial therapy based on age and risk factors must be started promptly in patients with bacterial meningitis. In adults, the incidence of aseptic meningitis is 7. 6 cases per 100, 000 persons, and the most common etiologies are enterovirus, HSV, and varicella-zoster virus infections. Initial dose of 5 million units intravenously, then 2. 5 to 3 million units every four hours during the intrapartum period. In contrast to aseptic viral meningitis, neuropsychiatric symptoms often predominate in encephalitis, for example, anomia, hallucinations, psychosis, personality changes, and agitation. Viral meningitis is the infection of the central nervous system by enteroviruses that can cause the infection. Mollaret’s meningitis may be caused by herpes simplex Type II; acyclovir may play a role in prophylaxis and therapy. Suggested dose during viral attacks is 800 to 1200 mg a day taken in divided doses. Increasing the dose of acyclovir for the treatment of drug-resistant HSV infections is rarely successful because mutations in the thymidine kinase gene are responsible for drug resistance. If the cause of meningitis is the herpes virus, your doctor will recommend an antiviral medication like Acyclovir or Famciclovir to treat the infection – this may require an IV and hospitalization.

Aseptic Meningitis

Learn about Acute Bacterial Meningitis symptoms, diagnosis and treatment in the Merck Manual. HCP and Vet versions too! There is no specific treatment for viral meningitis, which is often mild. In some cases, acyclovir (Zovirax) may be used to treat meningitis from the herpes simplex virus, although it appears to have a positive effect only when given very early in the illness. Fungal meningitis is treated with long courses of high-dose IV antifungal medications.


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